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Di Piero Bosio
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  4. Phage therapies are incredibly promising.

Phage therapies are incredibly promising.

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  • Cykonotundefined Questo utente è esterno a questo forum
    Cykonotundefined Questo utente è esterno a questo forum
    Cykonot
    scritto su ultima modifica di
    #1

    Phage therapies are incredibly promising. By embracing bacteriophages in veterinary settings, we can limit the development of antibiotic resistance and even treat resistant infections.

    https://www.sciencedirect.com/science/article/pii/S0377840125001282

    Bacteriophages also have excellent potential when it comes to protecting crops, allowing us to continue minimizing labor w/ monocultures

    https://pmc.ncbi.nlm.nih.gov/articles/PMC9820149/

    The FDA allows phage therapies for animals and plants, but these biologics are not yet approved in humans

    Cykonotundefined 1 Risposta Ultima Risposta
    • Cykonotundefined Cykonot

      Phage therapies are incredibly promising. By embracing bacteriophages in veterinary settings, we can limit the development of antibiotic resistance and even treat resistant infections.

      https://www.sciencedirect.com/science/article/pii/S0377840125001282

      Bacteriophages also have excellent potential when it comes to protecting crops, allowing us to continue minimizing labor w/ monocultures

      https://pmc.ncbi.nlm.nih.gov/articles/PMC9820149/

      The FDA allows phage therapies for animals and plants, but these biologics are not yet approved in humans

      Cykonotundefined Questo utente è esterno a questo forum
      Cykonotundefined Questo utente è esterno a questo forum
      Cykonot
      scritto su ultima modifica di
      #2

      New medical technology can be more easily developed in a veterinary context, while still advancing human health goals. That said, there are paths forward to bring phage therapies to humans, allowing us to better deal with challenging bacterial pathogens.

      https://gmr.scholasticahq.com/article/117696-a-way-forward-for-phage-therapy-in-the-united-states

      mRNA therapies are now being developed for veterinary uses, which greatly benefits and accelerates the field. That said, bacteriophages can also be used to deliver vaccines / antigens:

      https://pmc.ncbi.nlm.nih.gov/articles/PMC7565293/

      Cykonotundefined 1 Risposta Ultima Risposta
      • Cykonotundefined Cykonot

        New medical technology can be more easily developed in a veterinary context, while still advancing human health goals. That said, there are paths forward to bring phage therapies to humans, allowing us to better deal with challenging bacterial pathogens.

        https://gmr.scholasticahq.com/article/117696-a-way-forward-for-phage-therapy-in-the-united-states

        mRNA therapies are now being developed for veterinary uses, which greatly benefits and accelerates the field. That said, bacteriophages can also be used to deliver vaccines / antigens:

        https://pmc.ncbi.nlm.nih.gov/articles/PMC7565293/

        Cykonotundefined Questo utente è esterno a questo forum
        Cykonotundefined Questo utente è esterno a questo forum
        Cykonot
        scritto su ultima modifica di
        #3

        Bacteriophages can be a critical part of a holistic strategy for sustainable development. More generally, agroecology is necessary for continued human thriving.

        https://www.frontiersin.org/journals/sustainable-food-systems/articles/10.3389/fsufs.2024.1405409/full

        Holistic approaches to human health are also necessary to avoid disruptive crises such as COVID. While I would love everyone to become vegan and eliminate the environmental & health costs imposed by our system of factory farming, embracing holistic approaches can limit risks & enhance health technology.

        Cykonotundefined 1 Risposta Ultima Risposta
        • Cykonotundefined Cykonot

          Bacteriophages can be a critical part of a holistic strategy for sustainable development. More generally, agroecology is necessary for continued human thriving.

          https://www.frontiersin.org/journals/sustainable-food-systems/articles/10.3389/fsufs.2024.1405409/full

          Holistic approaches to human health are also necessary to avoid disruptive crises such as COVID. While I would love everyone to become vegan and eliminate the environmental & health costs imposed by our system of factory farming, embracing holistic approaches can limit risks & enhance health technology.

          Cykonotundefined Questo utente è esterno a questo forum
          Cykonotundefined Questo utente è esterno a questo forum
          Cykonot
          scritto su ultima modifica di
          #4

          Integrative approaches to public health will be critical going forward. One must view human health and immunity holistically: when America pulls back from our campaigns against pathogens like Tuberculosis in the global south, we create a space in which dangerous evolutionary developments can occur. We're ALL better off for eliminating polio around the world. That pathogen can no longer evolve & change & tax our society in so so many ways.

          Cykonotundefined 1 Risposta Ultima Risposta
          • Cykonotundefined Cykonot

            Integrative approaches to public health will be critical going forward. One must view human health and immunity holistically: when America pulls back from our campaigns against pathogens like Tuberculosis in the global south, we create a space in which dangerous evolutionary developments can occur. We're ALL better off for eliminating polio around the world. That pathogen can no longer evolve & change & tax our society in so so many ways.

            Cykonotundefined Questo utente è esterno a questo forum
            Cykonotundefined Questo utente è esterno a questo forum
            Cykonot
            scritto su ultima modifica di
            #5

            While mRNA technology can rapidly respond to developing threats, prevention is far more effective & efficient. Additionally, maintaining capacity for defense purposes is not feasible when you consider the scale and diversity of potential biological attacks — effective strategic competition requires POSITIVE engagement, not simple aggression which threatens to pull us into an escalatory race to the bottom.

            Bring back USAID. It boosts national security & is moral.

            Cykonotundefined 1 Risposta Ultima Risposta
            • Cykonotundefined Cykonot

              While mRNA technology can rapidly respond to developing threats, prevention is far more effective & efficient. Additionally, maintaining capacity for defense purposes is not feasible when you consider the scale and diversity of potential biological attacks — effective strategic competition requires POSITIVE engagement, not simple aggression which threatens to pull us into an escalatory race to the bottom.

              Bring back USAID. It boosts national security & is moral.

              Cykonotundefined Questo utente è esterno a questo forum
              Cykonotundefined Questo utente è esterno a questo forum
              Cykonot
              scritto su ultima modifica di
              #6

              Fungal infections can be incredibly difficult to treat, in part because they're difficult to target with current therapies — fungi are more molecularly similar to animals than bacteria are, so small-molecule therapies which do not harm the animal host are difficult to come by. That said, mycoviruses are viruses which DO target fungi. These viruses have potential therapeutic uses in humans and agriculture, just like bacteriophages.

              https://biomedres.us/fulltexts/BJSTR.MS.ID.008135.php

              Cykonotundefined 1 Risposta Ultima Risposta
              • Cykonotundefined Cykonot

                Fungal infections can be incredibly difficult to treat, in part because they're difficult to target with current therapies — fungi are more molecularly similar to animals than bacteria are, so small-molecule therapies which do not harm the animal host are difficult to come by. That said, mycoviruses are viruses which DO target fungi. These viruses have potential therapeutic uses in humans and agriculture, just like bacteriophages.

                https://biomedres.us/fulltexts/BJSTR.MS.ID.008135.php

                Cykonotundefined Questo utente è esterno a questo forum
                Cykonotundefined Questo utente è esterno a questo forum
                Cykonot
                scritto su ultima modifica di
                #7

                As global warming leads more fungi to adapt to living at temperatures found in the human body, it is thought that fungal infections may become more pervasive

                https://pmc.ncbi.nlm.nih.gov/articles/PMC11034633/

                Developing mycoviral therapy technology now will help protect us & our food systems in this changing world

                https://www.sciencedirect.com/science/article/pii/S2773078625000196

                Ecological approaches to health are critical for the prevention of future crises. By developing technologies to protect our food system, we can accelerate their development for humans

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